Calcium Fructoborate Nanoparticles: Plant-Based Carrier Boron as Potential Medicine for Neutron Cancer Therapy
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICESIT01_091
تاریخ نمایه سازی: 6 بهمن 1397
Abstract:
Boron neutron capture therapy (BNCT) is efficient therapeutic methods in cancer treatment based on nuclear capture and fission reactions. In this method, use of the best boron-containing agents for boron therapy and boron delivery agent for delivery of them to the infectious site are key points in therapy efficiency. Our research indicated that calcium fructoborate was the best compound as a boron-containing agent for boron therapy. Furthermore, studies have demonstrated that liposomes can effectively and selectively deliver large quantities of boron to tumors and that the compounds delivered by liposomes have a longer tumor retention time. Indeed, liposomal encapsulation of calcium fructoborate has been extensively evaluated as nanovehicles for the delivery of boron compounds for BNCT.In this paper, we deeply investigate molecular composition of the calcium fructoborate used as a carrier supplement for cancer therapy, by using FT-IR, XRD, TG, DSCand Raman spectroscopic analysis. The experimental measurements agree very wellwith the molecular formula Ca[(C6H10O6)2B]24H2O
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Authors
Faeqeh Pirouz
Faculty of Chemical Engineering, Babol Noshirvani University of Technology, Babol, Iran
Ghasem Najafpour
Faculty of Chemical Engineering, Babol Noshirvani University of Technology, Babol, Iran
Mohsen Jahanshahi
Faculty of Chemical Engineering, Babol Noshirvani University of Technology, Babol, Iran
Mazyar Sharifzadeh Baei
Department of Chemical Engineering, Islamic Azad University, Amol, Iran