Synthesis and characterization of gadolinium complexes with application contrast agent

MAGNEVIST Injection is the N- methylglucamine salt of the gadolinium complex of diethylenetriamine pentaacetic acid, and is an injectable contrast medium for magnetic resonance imaging (MRI). Contrast agents are commonly used to improve the visibility of abnormal structures or lesions in the body. Gadolinium-containing MRI contrast agents are aqueous solutions that are injected into the body to improve the image quality and allow a more accurate picture to be observed. Each mL of MAGNEVIST Injection contains 469.01 mg gadopentetate dimeglumine, 0.99 mg meglumine, 0.40 mg diethylenetriamine pentaacetic acid and water for injection.