Investigation of the Electrochemical behavior of Dipyridamole Drug in the presence of Methylthiouracil (MTU)

The electrochemical oxidation of dipyridamole drug in the presence of methylthiouracil (MTU) was studied by cyclic voltammetry and controlled potential coulometry on platinum electrode in ethanol/acetonitrile (1:4) as solvent[1]. The results show a two-step oxidation and a two-step reduction in reverse scan as counterparts. Bulk electrolysis of dipyridamole in constant potential demonstrated a 2 electron oxidation process.Voltammetry and coulometry investigations of oxidation of dipyridamole in the presence of MTU confirm attack of MTU to oxidized form of dipyridamole, to form a new product via an EC electrochemical mechanism[2,3].was performed in these solvents and the progress of the oxidation reaction as a function of time was monitored through cyclic voltammetry.