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Title

One-pot synthesis of isoxazole-5(4H)-ones via three-component condensation of β-keto esters, hydroxylamine hydrochloride, and substituted benzaldehydes in the presence of iodine in water

Year: 1397
COI: MCIS04_012
Language: EnglishView: 325
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Authors

Hanieh Ostadzadeha - School of Chemistry, Damghan University,
Hamzeh Kiyania - School of Chemistry, Damghan University,

Abstract:

In the present work, highly efficient method for the synthesis of 3-substituted-4-arylmethylidene-isoxazol- 5(4H)-one heterocyclic compounds by the three-component reaction between substituted benzaldehydes, β-keto esters, and hydroxylamine hydrochloride under the influence by iodine as commercially available, inexpensive, and easy to handle catalyst has been described. The benefits of this method are good yields, relatively shorter reaction times, simplicity of implementation, using water as the solvent, and respect of the environment.

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This Paper COI Code is MCIS04_012. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/839122/

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Ostadzadeha, Hanieh and Kiyania, Hamzeh,1397,One-pot synthesis of isoxazole-5(4H)-ones via three-component condensation of β-keto esters, hydroxylamine hydrochloride, and substituted benzaldehydes in the presence of iodine in water,Fourth National Conference on Materials Engineering, Chemical Engineering and Industrial Safety,Esfarayen,https://civilica.com/doc/839122

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Type of center: دانشگاه دولتی
Paper count: 1,479
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