Afshin Fathi - Pediatric Department, Bouali Children’s Hospital, Ardabil University of Medical Sciences (ARUMS)
Reza Maskani - Pediatric Department, Bouali Children’s Hospital, Ardabil University of Medical Sciences (ARUMS)
Sonia Hosseini Anbaran - Department of Medical,Ardabil Branch, Ardabil University of Medical Sciences (ARUMS)

Giant cell tumor of bone (GCTB) is benign but locally aggressive bone tumor of young adults. It typically presents as large lytic mass at the end of the epiphysis of long bones. Grossly it is comprised of cystic and hemorrhagic areas with little or no periosteal reaction(1) Giant cell tumor of talus is rare entity. In contrast to GCT of long bones, most cases occur in younger age group and tend to be multicentric(2)we report one case of giant cell rich osteosarcoma of talus bone in 11 years old Iranian girl in December 2017 that presented with tenderness of the left ankle after minor trauma with tumoral lesion in Tc99m-MDP scan.biopsy of talus lesion reported giant cell tumor with focal atypical chondroid and osteoid differentiation highly suggestive of low grade giant cell rich osteosarcoma.neoadjuvant chemotherapy with cisplatin 80mg and Adriamycin 50mg was begin for her

Giant cell tumor, bone, osteosarcoma