Investigation of antimicrobial properties of nhexane extract of Onosmastraussii

Onosma is an important genus of Boraginaceae family. Lipophilic extracts of roots of various species of this genus are used for wound and burns healing in west regions of Iran, of them Lorestan, for decades. The positive effect of this extracts is for their antimicrobial properties. In this study, using disk diffusion method, the effect of n-hexane extract of Onosmastraussii root on Acinetobacter baumannii, Bacillussubtilis, Staphylococcusaureus and Pseudomonasaeruginosa bacteria and Aspergillusflavus, Candidaalbicans and Fusariumsolani was investigated. Our results showed that the extract inhibits S. aureus, A.baumannii, P. aeruginosa, A. flavus and C. albicans growth, but not about B. subtilis and F. solani. This is the first investigation about antimicrobial effects of n-hexane extract of O. straussii.

Keywords:

Staphylococcusaureus , Acinetobacter baumannii , Pseudomonasaeruginosa , n-hexane extract , Onosma