Samaneh Chaharmiri Dokhaharani - Department of Biotechnology, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran
Masoomeh Ghobad-Nejhad - Department of Biotechnology, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran
Abbas Farazmand - Department of Biotechnology, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran
Hamid Moghimi - Department of Microbial Biotechnology, School of Biology, College of Science, University of Tehran, Tehran, Iran

Some polypore fungi have diverse pharmaceutical and medical applications. Since Staphylococcus aureus and Pseudomonas aeruginosa are major causes of hospitalacquired infection (HAI) and raise antibiotic-resistant isolates, the aim of this study was to assess the antibacterial effect of the polypore fungus Phellinus sp.methanolic extract against these bacteria. Phellinus sp. was collected in November 2017 from Mazandaran forests.The methanolic extract of the fruiting body of Phellinus sp.was prepared by maceration method. Then the antibacterial activity of the extract was evaluated by the broth micro dilution method against S. aureus ATCC25923 and P.aeruginosa ATCC9027. The MIC of the methanolic extract of Phellinus sp. against S. aureus and P. aeruginosa were 0.7, 1.5 mg/ml, and the MBC of that were 6.25, 12.5 mg/ml. The results of this study showed that methanolic extract of Phellinus sp. has antibacterial activity. It is concluded that the studied polypore fungus may be a source of antibacterial agent and more studies about its antibacterial properties is required.

Antibacterial, Phellinus sp., Polypore fungus