Synthesis a new series of potential biological activities compounds by reaction of imidoyl chlorides and GBP drug

Gabapentin (GBP) is used as an anticonvulsant drug which displays analgesic effects in the therapy of a variety of chronic pain conditions, such as complex regional pain syndrome, inflammatory pain, central pain, trigeminal neuralgia, diabetic neuropathy, headaches, malignant pain, post-herpetic neuralgia, and HIV related neuropathy [1]. Fluorinated of imidoyl halides became a versatile tool in the synthesis of various and important fluorinecontaining molecules [2]. In the present work we synthesized a new series of potential biological activities compounds 3 by reaction of imidoyl chlorides 2 and GBP drug 1. The structures of products were proved by 1H-NMR, 13C-NMR and IR spectral data and elemental analysis