Synthesis a new series of potential biological activities compounds by reaction of imidoyl chlorides and GBP drug
Publish place: 20th Iranian Chemical Congress
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
View: 379
متن کامل این Paper منتشر نشده است و فقط به صورت چکیده یا چکیده مبسوط در پایگاه موجود می باشد.
توضیح: معمولا کلیه مقالاتی که کمتر از ۵ صفحه باشند در پایگاه سیویلیکا اصل Paper (فول تکست) محسوب نمی شوند و فقط کاربران عضو بدون کسر اعتبار می توانند فایل آنها را دریافت نمایند.
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
IRANCC20_233
تاریخ نمایه سازی: 28 اردیبهشت 1398
Abstract:
Gabapentin (GBP) is used as an anticonvulsant drug which displays analgesic effects in the therapy of a variety of chronic pain conditions, such as complex regional pain syndrome, inflammatory pain, central pain, trigeminal neuralgia, diabetic neuropathy, headaches, malignant pain, post-herpetic neuralgia, and HIV related neuropathy [1]. Fluorinated of imidoyl halides became a versatile tool in the synthesis of various and important fluorinecontaining molecules [2]. In the present work we synthesized a new series of potential biological activities compounds 3 by reaction of imidoyl chlorides 2 and GBP drug 1. The structures of products were proved by 1H-NMR, 13C-NMR and IR spectral data and elemental analysis
Authors
Zahra Rezaei
Department of Organic Chemistry, Faculty of Chemistry, Vali-e-Asr University, Rafsanjan, ۷۷۱۷۶, Iran
Ali Darehkordi
Department of Organic Chemistry, Faculty of Chemistry, Vali-e-Asr University, Rafsanjan, ۷۷۱۷۶, Iran
Fariba Rahmani
Department of Organic Chemistry, Faculty of Chemistry, Vali-e-Asr University, Rafsanjan, ۷۷۱۷۶, Iran