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Synthesis a new series of potential biological activities compounds by reaction of imidoyl chlorides and GBP drug

عنوان مقاله: Synthesis a new series of potential biological activities compounds by reaction of imidoyl chlorides and GBP drug
شناسه ملی مقاله: IRANCC20_233
منتشر شده در بیستمین کنگره شیمی ایران در سال 1397
مشخصات نویسندگان مقاله:

Zahra Rezaei - Department of Organic Chemistry, Faculty of Chemistry, Vali-e-Asr University, Rafsanjan, ۷۷۱۷۶, Iran
Ali Darehkordi - Department of Organic Chemistry, Faculty of Chemistry, Vali-e-Asr University, Rafsanjan, ۷۷۱۷۶, Iran
Fariba Rahmani - Department of Organic Chemistry, Faculty of Chemistry, Vali-e-Asr University, Rafsanjan, ۷۷۱۷۶, Iran

خلاصه مقاله:
Gabapentin (GBP) is used as an anticonvulsant drug which displays analgesic effects in the therapy of a variety of chronic pain conditions, such as complex regional pain syndrome, inflammatory pain, central pain, trigeminal neuralgia, diabetic neuropathy, headaches, malignant pain, post-herpetic neuralgia, and HIV related neuropathy [1]. Fluorinated of imidoyl halides became a versatile tool in the synthesis of various and important fluorinecontaining molecules [2]. In the present work we synthesized a new series of potential biological activities compounds 3 by reaction of imidoyl chlorides 2 and GBP drug 1. The structures of products were proved by 1H-NMR, 13C-NMR and IR spectral data and elemental analysis

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/850867/