Synthesis of azo compounds by reaction between trifluoroacetimidoyl chlorides and hydrazinhydrat

Trifiuoromethylated compounds have been receiving great interest in medicinal,agricultural, and material sciences [1]. Among the various trifluoromethylations, thepreparation and utilization of trifluoromethylated building blocks involve one of the useful approaches to the goal, and have currently been receiving interest in syntheticorganofluorine chemistries [2]. Azo compounds are the most common synthetic colourings used in foods, pharmaceuticals and cosmetics. Although they have been used in this way for many years, comparatively little work on their toxicity or metabolism was published before the last decade. With the increasing awareness of possible health hazards associated with their use, however, more attention has been focused recently on the biological activity of azo compounds [3]. Here we wish to report the result of our study on the reaction of trifluoroacetimidoyl chlorides 1 with NH2NH2.H2O 2 in the presence of base lead to azo-compounds 3. The structures of this products were proved by 1H-NMR, 13C-NMR and IR spectral data and elemental analysiss.