Iraj Sarvi - Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran
Mostafa Gholizadeh - Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran
Mohammad Izadyar - Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran

It is well-known that palladium-catalyzed coupling reactions are very important and powerful methodologies in the synthetic organic chemistry [1]. Among them, the Suzuki reaction is one of the most versatile methods for the synthesis of a variety of biaryls and alkenes via C-C bond formation. Our aim has been to investigate designing of the efficient catalytic system with high activity for Suzuki cross-coupling reaction with minimum by-products in green media. Herein, we report our work on impregnating Pd nanoparticles into epichlorohydrin and aminoguanidinefunctionalized Silica coated Fe3O4 magnetic nanoparticles as an efficient catalyst for Suzuki reaction in water. Magnetic nanoparticles coated by aminoguanidine were used for selective adsorption of acid dyes from aqueous solution which was reported previously [2]. However, to the best of our knowledge, there has been no report about the heterogeneous magnetic Pd/epichlorohydrin-aminoguanidine (EP-AG) catalyst for Suzuki cross coupling reaction. The FeS-EP-AG-Pd nanocatalyst was prepared in 4 steps: in the first step the Fe3O4@SiO2 magnetic nanoparticles was prepared by Stöber method, in step 2, EP-AG linker as novel designed ligand bonded on the surface of FeS nanoparticles. In step 3, Pd(OAc)2 was complexed to this ligand. Finally, Pd nanoparticles were generated via NaBH4 reduction procedure. A schematic pathway of FeS@EP-AG-Pd catalyzed Suzuki cross-coupling reaction is shown in Fig. 1.