Fe3O4@C-SO3H: Synthesis, Characterization and Its application on benzo[4, 5]imidazo[1, 2-a]-pyrimidines synthesis

The magnetic Fe3O4@C-SO3H nanoparticle (MNPs) was widely studied and showed high catalytic activities in many chemical reactions [1-4]. In this report, a sulfonic acid-functionalized magnetic nanoparticle (Fe3O4@C-SO3H) was successfully prepared using Sucrose via a solvothermal process. The sulfonic acid-functionalized Fe3O4@C-SO3H magnetic nanoparticle was obtained by grafting the sulfonic groups on the surface of Fe3O4@C nanoparticles in the presence of p-Toluenesulfonic. The magnetic Fe3O4@C-SO3H nanoparticle was used as an efficient and new catalyst for the one-pot synthesis of benzo[4, 5]imidazo[1, 2-a]-pyrimidine derivatives through the condensation of aldehyde, β-dicarbonyl compounds and 2-aminobenzimidazole under solvent-free conditions in excellent yields. High catalytic activity and easy magnetically separation from reaction media are two important factors for evaluating the performance of Fe3O4@C-SO3H nanoparticles in the preparation of pyrimidine derivatives