Synthesis of 1-amidoalkyl-2-phenols using a novel nanomagnetic catalyst with Cl[DABCO-NO2]C(NO2)3 tags under mild conditions

1-Amidoalkyl-2-naphthols are paramount important organic compounds as they can be easily converted to 1-aminoalkyl-2-naphthols via hydrolysis, which are biologicallyimportant compounds. 1-Aminoalkyl-2-naphthols have been used as Brady cardiac and hypotensive agents [1]. Moreover, 1-amidoalkyl-2-naphthols can be converted to1,3-oxazine derivatives [2]. 1,3-Oxazine derivatives have pharmaceutical and biological properties such as anti-tumor, anticonvulsant, antimalarial, analgesic, antibiotic, antianginal, antirheumatic and antihypertensive [3]. So, improvement in 1- amidoalkyl-2-naphtols synthesis methodology is important. Herein, we introduce Fe2O3@SiO2(CH2)3-Cl[DABCO-NO2]C(NO2)3 as a novel nanomagnetic catalyst and use it as an efficient and reusable catalyst in the synthesis of 1-amidophenol-2-naphtols under solvent-free condition.