Nano magnetite supported iron–phthalocyanine as a promising catalyst for the synthesis of β-amido ketones

β-Amido ketones are precursors for synthesis of heterocycles, β-amino ketones and β-amino alcohols which are important units in biological compounds such as antibiotic and neopolyoxines [1]. Recently, nanoparticles have attracted attention due to their exclusive features. Owning high surface area, high density of active sites and excellent accessibility, nanomaterials have found use as efficient semiheterogeneous catalyst in various reactions [2]. Metallophthalocyanines are metalorganic compounds exhibit special physical and chemical properties such as thermal stability, resistance to atmospheric oxidation electrical conductivity, light fastness and inertness to acids and alkalis [3]. In this research, we hope to report the preparation of some new β-amido ketones from acetophenone, benzyl cyanide, acetyl chloride and various aromatic aldehydesin the presence of Fe3O4@SiO2-GA-FePc as a heterogamous catalyst at 70o C (Scheme 1). The products have been obtained in high yields and short reaction times. The structure of products has been assigned by nuclear magnetic resonance (NMR) and infrared (IR) together with physical and other spectroscopic data.