One-pot Synthesis of quinoxaline Derivatives via Palladium-catalyzed reactions
Publish place: 20th Iranian Chemical Congress
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
View: 229
متن کامل این Paper منتشر نشده است و فقط به صورت چکیده یا چکیده مبسوط در پایگاه موجود می باشد.
توضیح: معمولا کلیه مقالاتی که کمتر از ۵ صفحه باشند در پایگاه سیویلیکا اصل Paper (فول تکست) محسوب نمی شوند و فقط کاربران عضو بدون کسر اعتبار می توانند فایل آنها را دریافت نمایند.
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
IRANCC20_714
تاریخ نمایه سازی: 28 اردیبهشت 1398
Abstract:
The pyrrolo[1,2-a]quinoxaline skeleton is present in various heterocyclic compounds possessing interesting biological activities. Quinoxaline derivatives display a broadspectrum of biological activities including anti-microbial,[1] anti-inflammatory [2] and anticancer [3] properties. A literature survey shows that the synthesis of quinoxalines,starting from the quinoxaline moiety, has been under explored. Consequently, the development of new synthetic strategies for the synthesis of quinoxaline derivativesfrom the quinoxaline scaffold are important. In this research work, new quinoxalines were synthesized through the multicomponent reaction of 3-substituted 2-chloroquinoxalines, benzoic acids and propargyl bromide in the presence of a palladium-copper catalytic system. This onepot process provided an efficient and successful approach for the construction of 1,4- disubstituted quinoxalines with good-to-high yields. All the new synthesized compounds were characterized by the analytical spectral data
Authors
Sima Abbaspour
Department of Chemistry, Shahrood University of Technology, Shahrood, Iran;
Ali Keivanloo
Department of Chemistry, Shahrood University of Technology, Shahrood, Iran;
Mohammad Bakherad
Department of Chemistry, Shahrood University of Technology, Shahrood, Iran;