Synthesis of Xanthene and Dihydroquinazolin-4(1H)-ones by fructose catalyst
Publish place: 20th Iranian Chemical Congress
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
View: 262
متن کامل این Paper منتشر نشده است و فقط به صورت چکیده یا چکیده مبسوط در پایگاه موجود می باشد.
توضیح: معمولا کلیه مقالاتی که کمتر از ۵ صفحه باشند در پایگاه سیویلیکا اصل Paper (فول تکست) محسوب نمی شوند و فقط کاربران عضو بدون کسر اعتبار می توانند فایل آنها را دریافت نمایند.
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
IRANCC20_782
تاریخ نمایه سازی: 28 اردیبهشت 1398
Abstract:
Xanthene, Benzoxanthene and 2-Amino-chromene and its derivatives represent an important class and very useful compounds in various fields of chemistry. These molecules are biologically active and find application in pharmacological, medicinal [1]. Also, Dihydroquinazolin-4 (1H) -ones constitute an important class of heterocycliccompounds that have been widely exhibited spectrum of biological, physiological activities and pharmacological properties [2], such as anticancer, antidiuretic, anticonvulsant, antibacterial, antifungal activity [3] and mono-amine oxidase inhibition and are also used as 5-hydroxytryptamine (5-HT) receptor ligands. Recently,Lindsley and coworkers observed the metabotropic glutamate receptor (mGluR) properties of this class of compounds. In this project, sulfonated fructose used as a new, non-toxic and effective catalyst for benzaldehyde, 2-naphthol and dimedone for the synthesis of tetrahydrobenzo [a] xanthene-11-one and the reaction of aldehyde and 2-naphthol to synthesize 14H-DI benzo [a, j] Xanthene. Advantages of this method are: the use of inexpensive, affordable and non-toxic catalyst, high efficiency, relatively short response times, simple product purifications, good to excellent yields.
Authors
Ashraf Moradi
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran
Ali Kakeshpour
Department of Chemistry, Faculty of Science, University of Tehran, Tehran, Iran
Fatemeh Pirani
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran