Publisher of Iranian Journals and Conference Proceedings

Please waite ..
CIVILICAWe Respect the Science
Publisher of Iranian Journals and Conference Proceedings
عنوان
Paper

Epigenetic Tools in Early Diagnosis and Management of Gastrointestinal Cancers: The Role of micro RNAs

تعداد صفحات: 2 | تعداد نمایش خلاصه: 120 | نظرات: 0
سال انتشار: 1397
کد COI Paper: IPMCMED03_027
زبان Paper: Englishglish
نسخه کامل Paper در کنفرانس ارائه نشده است و در دسترس نیست.

مشخصات نویسندگان Paper Epigenetic Tools in Early Diagnosis and Management of Gastrointestinal Cancers: The Role of micro RNAs

L Alimardanian - PhD, SRBIAU, Department of molecular genetics
K Banihashemi - MD, Academic Member, Department of Medical Sciences, IIER and ATU, Ministry of Science, Research and Technology, Tehran, Iran
P Ebrahimi - PhD, Parseh Medical Genetics Clinic
S Aboiie Mehrizii - MD, Parseh Medical Genetics Clinic

چکیده Paper:

Gastrointestinal Cancers has been considered as one of the most important malignancies in the world. Early cancer detection and monitoring of its consequences is the primary determinant which need reliable and precise profile of diagnostic and follow up markers. By discovering the role of some Micro RNA molecules (miRNAs) in the pathogenesis and process of the disorders, they now considered as relatively reliable markers and many scientific centers select the miRNAs as being a part of their investigations.Material and methodsAs a meta-Analysis by Comparing the literatures, one may notice there many different miRNAs with various expression patterns during initiation and progress of gastrointestinal cancers which constituted our approach to a set of epigenetic markers in early diagnosis and follow up of the these malignancies. In this study, biochemical availability, stability and relevance of the selected micro RNA molecules have been compared to make a relatively reliable and precise miRNA integrated proposed profile as a complementary tool for diagnosis and follow up of the disease. Results and Discussion As an integrated early diagnostic and follow up miRNA profiles, we classified different sets of these biomarkers including a set of let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer. The proposed profile associates with up and down plasma titer patterns in each stage of initiation and progression of gastric and esophageal cancers. These miRNA biomarkers proposed profile could be considered as relatively suitable systematic screening and monitoring profile for physicians in their clinical practice.

کلیدواژه ها:

Micro RNAs, Gastrointestinal cancers, Epigenetic Biomarkers

کد Paper/لینک ثابت به این Paper

برای لینک دهی به این Paper می توانید از لینک زیر استفاده نمایید. این لینک همیشه ثابت است و به عنوان سند ثبت Paper در مرجع سیویلیکا مورد استفاده قرار میگیرد:

https://civilica.com/doc/858168/

کد COI Paper: IPMCMED03_027

نحوه استناد به Paper:

در صورتی که می خواهید در اثر پژوهشی خود به این Paper ارجاع دهید، به سادگی می توانید از عبارت زیر در بخش منابع و مراجع استفاده نمایید:
undefined, undefined و undefined, undefined و undefined, undefined و undefined, undefined,1397,Epigenetic Tools in Early Diagnosis and Management of Gastrointestinal Cancers: The Role of micro RNAs,سومین کنگره بین المللی پزشکی شخصی ایران,Tehran,,,https://civilica.com/doc/858168

در داخل متن نیز هر جا که به عبارت و یا دستاوردی از این Paper اشاره شود پس از ذکر مطلب، در داخل پارانتز، مشخصات زیر نوشته می شود.
برای بار اول: (1397, Alimardanian, L؛ K Banihashemi و P Ebrahimi و S Aboiie Mehrizii)
برای بار دوم به بعد: (1397, Alimardanian؛ Banihashemi و Ebrahimi و Aboiie Mehrizii)
برای آشنایی کامل با نحوه مرجع نویسی لطفا بخش راهنمای سیویلیکا (مرجع دهی) را ملاحظه نمایید.

Research Info Management

Certificate | Report Paper
این Paper در بخشهای موضوعی زیر دسته بندی شده است:
  • علوم پزشکی > سرطان
  • Export Citation info of this Paper to research management softwares

    New RelatedPapers

    Share this paper

    WHAT IS COI?

    COI is a national code dedicated to all Iranian Conference and Journal Papers. the COI of each paper can be verified online.

    Support