Antibacterial chitosan/polyethylene oxide nanofibrous mats

Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:

NICEC16_080

تاریخ نمایه سازی: 7 خرداد 1398

Abstract:

The ZIF-8 nanoparticles were synthesized and applied for the fabrication of electrospun CS-PEO nanofibrous mats containing three different weight percents (3, 5 and 10%) of ZIF-8 NPs. The CSPEO- GA-3% ZIF-8 NPs crosslinked with glutaraldehyde (GA) vapor was also prepared in order to examine its properties and compare the results with those of non-crosslinked sample. According to the FE-SEM images, the spherical ZIF-8 NPs were ~60 nm in size and all of the nanofibers had average diameters of ~70–100 nm. Water contact angle test illustrated that the hydrophobicity of the CS-PEO-3% ZIF-8 NPs mat was the highest among other mats. Surprisingly, the CS-PEO-3% ZIF- 8 mat exhibited 100% antibacterial activity against both the Gram-positive Staphylococcus aureus and Gram-negative Escherchial coli bacteria. Finally, the CS-PEO-3% ZIF-8 NPs mat was considered as the most preferred sample for food coating/packaging applications due to its highest hydrophobicity as well as appropriate thermal and tensile properties.

Keywords:

Antimicrobial activity , Electrospinning , Chitosan–polyethylene oxide nanofibrous mat.

Authors

Negar Pourzadi

Department of Chemistry, Amirkabir University of Technology (Tehran Polytechnic), P.O. Box:۱۵۸۷۵-۴۴۱۳, Tehran, Iran.

Zahra Shariatinia

Department of Chemistry, Amirkabir University of Technology (Tehran Polytechnic), P.O. Box:۱۵۸۷۵-۴۴۱۳, Tehran, Iran.

Iraj Kohsari

Department of Chemistry, Amirkabir University of Technology (Tehran Polytechnic), P.O. Box:۱۵۸۷۵-۴۴۱۳, Tehran, Iran.