Synthesis, characterization, antibactrial activities of Ag(I) complex containing the SpymMe2= 4,6-dimethyle-2-mercaptopyrmidine and interaction Between Ag(I) complex with salmon fish DNA

Human beings are often infected by microorganisms such as bacteria, yeasts, and viruses in the living environment. Resistance to antimicrobial agents by pathogenic bacteria has emerged in recent years and is a major health problem. Research in antibacterial material containing various natural and inorganic substances has been intensive. Since silver has antimicrobial properties [1] , we prepared the new complex of Ag with ligand 4,6-dimethyle-2-mercaptopyrmidine, which were characterized by spectroscopies and electrochemical techniques and elemental analysis [ 2 ] . Additionally, in this research antibacterial activity of this Ag against the Bactria’s of Staphylococcus aureus and Escherichia coli been investigated. Finally, the binding properties of Ag(I) with salmon fish DNA was investigated by UV-Vis spectroscopy and Kb=1.2×105 was obtained