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Synthesis, characterization and DNA-binding studies of a metal complexes of anthranilic acid

عنوان مقاله: Synthesis, characterization and DNA-binding studies of a metal complexes of anthranilic acid
شناسه ملی مقاله: IICC20_064
منتشر شده در بیستمین سمینار شیمی معدنی ایران در سال 1397
مشخصات نویسندگان مقاله:

Mahin Namroudi, - Department of Chemistry, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran
Niloufar Akbarzadeh- T - Department of Chemistry, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran
Tahere Kondori - Department of Chemistry, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran

خلاصه مقاله:
The project first synthesizes, detects and investigates the spectroscopy of complexes of Ni, Cu and Zn binomial intermediates with anthranilic acid ligands. Synthesized complexes characterized using FT-IR, UV-vis and 1H-NMR. The electron spectra of these complexes have absorption bands in the region of 200-400 nm and intra-ligand transitions (n → π *, π → π *) of anthranic acid. Bands in the range of 400-800 nm attributed to d-d transitions. The results obtained from the 1H NMR study are also consistent with the theoretical results [1]. Investigation of the interaction of synthetic complexes with DNA at 298, 300 and 310 Kelvin temperatures was carried out using electron-absorption spectrophotometry technique, and ?? was obtained for the bonding of the complex with DNA. The thermodynamic parameters, such as ΔG °, ΔH ° and ΔS °, were calculated [2].

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/876365/