Synthesis, characterization DNA / BSA interaction and antibacterial studies of Zn(II) N2O-Schiff base complex

Schiff base of ortho-phenylenediamine and acetylacetone alone and their Zn(II) complexes have a variety of biological applications including antibacteriale, antifungal, anticancer and other properties[1-3].The present investigation includes in situ synthesis of 4-(2-amino-phenylimino)-pentene-2-ol (acac-o-PhdaH) ligand and its Zn(II) complex. This complex of formula [Zn(acac-o-phdn)Cl] have been characterized by FT-IR , UV-Vis and 1H-NMR spectroscopic techniques and conductivity measurements. These studies showed coupling of 1:1 stoichiometric ratio of ortho-phenylenediamine and acetylacetone. DNA / BSA and antibacterial studies of the above mentioned Zn(II) complexes are in progress