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Title

Comparison of Nasal Non-invasive Ventilation Methods in Preterm Neonates with Respiratory Distress Syndrome

Year: 1397
COI: JR_IRJN-9-4_009
Language: EnglishView: 236
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Authors

ahmad shahfarhat - assistant professor, neonatologist, Neonatal Research Center, emam reza hospital, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran
Ashraf Mohammadzadeh - Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Gholam Ali Mamuri - Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Reza Saeidi - Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract:

Background: Humidified heated high flow nasal cannula (HHHFNC), nasal continuous positive airway pressure (NCPAP), and nasal intermittent positive pressure ventilation (NIPPV) are three nasal non-invasive ventilation methods. The purpose of this study was to compare these three methods in decreasing intubation and mechanical ventilation rate in preterm neonates with respiratory distress syndrome (RDS). Methods: This study was a randomized controlled study conducted on 160 neonates. The inclusion criteria for intubation in this study were persistent respiratory acidosis (arterial pH<7/2 or PCO2> 60), hypoxemia, severe and repeated apnea episodes which did not respond to increasing respiratory rate and therefore required ventilation. Cranial Ultrasound was performed on the third day after birth. The data of all neonates were collected until the day of discharge and analyzed by SPSS (version 20) and statistical methods. Results: Based on the results,there was no significant difference among the three randomized methods. Out of all the cases, 72% of the neonates with NIPPV had successful non-invasive ventilation (35/53), compared to 73/6% in NCPAP (39/53) and 72/2% in HHHFNC (P=0/999). Similarly, there was no significant difference among the three methods in total ventilation time and the need for supplemental oxygen. Conclusion: The use of HHHFNC at birth in preterm neonates with RDS is safer than the other two methods. However, it is not more effective than the other two methods in the reduction of intubation rate.

Keywords:

Keywords: Humidified heated high flow nasal cannula (HHHFNC) , Nasal continuous positive airway pressure (NCPAP) , Nasal intermittent positive pressure ventilation (NIPPV) , Preterm neonates , Respiratory distress (RDS)

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This Paper COI Code is JR_IRJN-9-4_009. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/887108/

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If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
shahfarhat, ahmad and Mohammadzadeh, Ashraf and Mamuri, Gholam Ali and Saeidi, Reza,1397,Comparison of Nasal Non-invasive Ventilation Methods in Preterm Neonates with Respiratory Distress Syndrome,https://civilica.com/doc/887108

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Type of center: علوم پزشکی
Paper count: 7,678
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