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Title

Extranodal NK/T Cell Lymphoma with Destruction of the Uvulae: A Case Report

مجله علمی گوش و حلق و بینی ایران، دوره: 29، شماره: 2
Year: 1396
COI: JR_IJOTO-29-2_007
Language: EnglishView: 307
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Authors

Farahzad Jabbari Azad - Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Zahra Delavarian - Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Science, Mashhad, Iran.
Masoud Hatami - Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Mashhad University of Medical Science, Mashhad, Iran.
Hosein Rahimi - Department of Hematology-Oncology, Mashhad University of Medical Science, Mashhad, Iran.

Abstract:

Introduction: Extranodal Natural Killer (NK)/T-cell lymphoma (NKTCL) nasal type is a rare but well-known disease with poor prognosis. NKTCL is more prevalent in Asia and comprises about 7-10% of all non-Hodgkin lymphoma cases in this region. The characteristic clinical pattern of NKTCL is the destruction of the midline structures of the mid-face. Case Report: The present study examines a case of NKTCL in a 23-year-old man with a destructive ulcer of the palate and uvulae. Based on immunohistochemical results, after three months of delay, the definitive diagnosis was revealed to be Extranodal NK/T cell lymphoma. Following the third cycle of chemotherapy, the patient died due to sepsis and infection. Conclusion: It is very common to misdiagnose NKTCL with other clinical conditions such as necrotizing stomatitis, deep fungal ulcers, Wegener’s Granulomatosis disease, etc. Delay in diagnosis can worsen the course of the disease and its prognosis.

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Jabbari Azad, Farahzad and Delavarian, Zahra and Hatami, Masoud and Rahimi, Hosein,1396,Extranodal NK/T Cell Lymphoma with Destruction of the Uvulae: A Case Report,https://civilica.com/doc/887358

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