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Title

A Cross Sectional Study of Opioid Poisoning in Children at a Tertiary Center

Year: 1395
COI: JR_PJMT-5-4_004
Language: EnglishView: 148
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Authors

Nosrat Ghaemi - Associate Professor of Pediatric Endocrinology, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Samaneh Alikhani - Pediatrician, Mashhad University of Medical Sciences, Mashhad, Iran
Sepideh Bagheri - Assistant professor of pediatrics, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Majid Sezavar - Fellowship of Pediatric Intensive Care, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract:

Background:Poisoning in children is a world-wide problem and one of the most important reasons for children’s hospital admission. Incidence of toxicity based on cultural and economic characteristics vary in different communities. Methods: All children with proven opioid toxicity who admitted to children emergency ward of Imam Reza hospital of Mashhad through June 2014 to June 2015 were included the study. Age, sex, weight, parent’s educational level and job, causes and kinds of ingested opioid, addiction in family, clinical manifestations, laboratory findings, changes in QT corrected (QTC), and mortality rate were recorded. Finally, all data were analyzed with SPSS. Results: In this study, 126 opioid-intoxicated children were recruited. No significant age difference was seen between genders (P value = 0.24). Parent s educational levels in most cases were low. Addiction to opium was also common among fathers (68.3%). Methadone was the most common agent causing opioid poisoning (52.4%), followed by opium (43.7%). The cause of poisoning was accidental in 58% of patients. The common signs and symptoms were drowsiness (77.8%), miotic pupil (69 %), decreased levels of O2 saturation (67.5%), Bradypnea (37.3%), apnea (27.8%) and convulsions (8.7%). Venous blood gases (VBG) in most cases (69.8%) was abnormal, leukocytosis (26.2%), hyperglycemia (11.1%), hyponatremia (9.5%), hypernatremia (5.6%), increases in distance of QT in Electrocardiography (2.4%) were seen. Conclusion:Opioid poisonings are severe and life-threatening in children. Methadone was the most common cause of poisoning in more than the half of cases (52.4%). Poisonings were due to low parental knowledge about methadone poisoning and careless storage of methadone at their home.

Keywords:

Children, Northeast of Iran, Opioid Drugs, Poisoning, Toxicity

Paper COI Code

This Paper COI Code is JR_PJMT-5-4_004. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/890634/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Ghaemi, Nosrat and Alikhani, Samaneh and Bagheri, Sepideh and Sezavar, Majid,1395,A Cross Sectional Study of Opioid Poisoning in Children at a Tertiary Center,https://civilica.com/doc/890634

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  • Okie S. A flood of opioids, a rising tide of ...
  • Bailey JE, Campagna E, Dart RC, RADARS System Poison Center ...
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  • Boyer EW. Management of opioid analgesic overdose. N Engl J ...
  • Zamani N, Sanaei-Zadeh H, Mostafazadeh B. Hallmarks of opium poisoning ...
  • Farnaghi F, Jafari N, Mehregan FF. Methadone poisoning among children ...
  • Baldacchino A, Arbuckle K, Petrie DJ, McCowan C. Neurobehavioral consequences ...
  • Gibson JC, Vulliamy A. Accidental methadone poisoning in children: A ...
  • Jabbehdari S, Farnaghi F, Shariatmadari SF, Jafari J, Mehregan FF, ...
  • Khajeh A, Narouie B, Noori NM, Emamdadi A, Rad MG, ...
  • Farzaneh E, Amani F, Mirzarahimi M, Nasrollahtabar M, Sayad Rezaei ...
  • Besharat S, Jabbari A, Besharat M. Opium as a Fatal ...
  • Anderson M, Hawkins L, Eddleston M, Thompson JP, Vale JA, ...
  • Arjmand Shabestari A, Purfarzad Z, Ghorbani M. Acute Poisoning in ...
  • Kadivar M, Javadinia N, Nemati N. A Survey on opium ...
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