Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها
Paper
Title

A systematic review and meta-analysis of clinical trials on saffron (Crocus sativus) effectiveness and safety on erectile dysfunction and semen parameters

Year: 1397
COI: JR_AJP-8-3_002
Language: EnglishView: 262
This Paper With 12 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 12 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:

Authors

Nahid Maleki-saghooni - Student Research Committee, Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
Khadijeh Mirzaii - Faculty of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
Hossein Hosseinzadeh - Pharmaceutical Research Center, Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
Ramin Sadeghi - Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract:

Objective: We performed this systematic review and meta-analysis study to determine saffron (Crocus sativus) effectiveness and safety in male infertility problems. Materials and Methods: The databases PubMed, Scopus, Cochrane, Google Scholar, SID, IranMedex and Magiran until July 2016 and reference section of relevant articles, were searched to find both English and Persian clinical trials on male infertility issues that used saffron as medical treatment. Also, the quality of these trials was evaluated by Oxford Center for Evidence Based Medicine checklist. A total of six trials was ultimately included. All statistical analyses were done by Comprehensive Meta-analysis (CMA) Version 2. Results: Only in one study conducted on sperm parameters, the mean percentage of sperm with normal morphology (p<0.001) and sperm motility (p<0.001) were increased. Quantitative analysis showed that saffron had a significantly positive effect on all dimensions of Erectile Function questionnaire (MD for Erectile function=5.36(p=0.00), Orgasmic function=1.12 (p=0.007), Overall satisfaction=1.23 (p=0.005), Satisfaction with intercourse=2.18 (p=0.00) and Sexual desire=0.78 (p=0.00), Fixed effects model using 3 trials). The result of subgroup analysis based on dimensions of Erectile Function questionnaire showed statistically significant differences among subgroups (p=0.00). Conclusion: saffron has a positive effect on erectile dysfunction. However, our study showed contradictory results about semen parameters. So, interpretation of results is limited because of methodological flaws of the included studies, erectile dysfunction status and a large heterogeneity among them. Further trials are still needed to confirm the current findings.

Keywords:

Paper COI Code

This Paper COI Code is JR_AJP-8-3_002. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/893590/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Maleki-saghooni, Nahid and Mirzaii, Khadijeh and Hosseinzadeh, Hossein and Sadeghi, Ramin,1397,A systematic review and meta-analysis of clinical trials on saffron (Crocus sativus) effectiveness and safety on erectile dysfunction and semen parameters,https://civilica.com/doc/893590

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :

  • Abdullaev F, and Espinosa-Aguirre J. 2004. Biomedical Properties of Saffron ...
  • Abdullaev  I. 2002. Cancer Chemopreventive and Tumoricidal Properties of Saffron ...
  • Agarwal A. and Said M. 2005. Oxidative Stress, Dna Damage ...
  • Alavizadeh H, and Hosseinzadeh H. 2014. Bioactivity Assessment and Toxicity ...
  • Andersson E. 2011. Mechanisms of Penile Erection and Basis for ...
  • Basker, D. &amp; Negbi, M. 1983. Uses of Saffron. Econ ...
  • Botsoglou  N, Florou-Paneri  P, Nikolakakis  I, Giannenas  I, Dotas  V ...
  • Burnett A. 2012. Evaluation and Management of Erectile Dysfunction. Wein ...
  • Chatterjee S, Poduval B, Tilak C, Devasagayam P. 2005. A ...
  • De Liz  T, and Strauss  B. 2005. Differential Efficacy of ...
  • Downey  J , Yingling  S , Mckinney  M , Husami  ...
  • Hamada A, Esteves  C, Nizza  M, Agarwal  A. 2012. Unexplained ...
  • Hatzimouratidis K, Amar E, Eardley  I, Giuliano  F, Hatzichristou  D, ...
  • Heidary M, Vahhabi S, Reza-Nejadi J, Delfan B, Birjandi M, ...
  • Heidelbaugh J. 2010. Management of Erectile Dysfunction. Am Fam Physician, ...
  • Hosseinzadeh  H, and Jahanian  Z. 2010. Effect of Crocus Sativus ...
  • Hosseinzadeh  H, and Nassiri‐Asl  M. 2013. Avicenna s (Ibn Sina) ...
  • Hosseinzadeh  H, Sadeghnia  R, Ghaeni    A, Motamedshariaty  S, Mohajeri  A. ...
  • Hosseinzadeh H, and  Younesi  M. 2002. Antinociceptive and Anti-Inflammatory Effects ...
  • Hosseinzadeh  H, Ziaee  T, Sadeghi A. 2008. The Effect of ...
  • Howick J, Chalmers I, Glasziou P, Greenhalgh T , Heneghan ...
  • Irani M, Amirian M, Sadeghi R, Le-Lez J,  Latifnejad-Roudsari R.2017.The ...
  • Isidori  M, Pozza C , Gianfrilli  D, Isidori A. 2006. ...
  • Kanakis  D, Tarantilis A , Tajmir-Riahi A, Polissiou G. 2007. ...
  • Khori V, Alizadeh  M, Yazdi  H, Rakhshan E, Mirabbasi  A, ...
  • Kumar R, Gautam G, Gupta  P. 2006. Drug Therapy for ...
  • Modabbernia  A, Sohrabi  H, Nasehi A, Raisi  F,Saroukhani S, Jamshidi ...
  • Mohammadzadeh-Moghadam H, Nazari    M, Shamsa  A, Kamalinejad  M, Esmaeeli  H, ...
  • Mollazadeh H, Emami  A, Hosseinzadeh H. 2015. Razi’s Al-Hawi and ...
  • Mosher  D. 1988. Fecundity and Infertility in the United States. ...
  • Mousavi Z, and Bathaie  Z. 2011. Historical Uses of Saffron: ...
  • Pham  Q, Cormier F, Farnworth E, Tong   H,Van Calsteren R. ...
  • Porst H, Padma-Nathan H, Giuliano F, Anglin G , Varanese ...
  • Rezaee R, and Hosseinzadeh H. 2013. Safranal: From an Aromatic ...
  • Rios  J, Recio  M, Giner  R, Manez  S. 1996. An ...
  • Safarinejad M , Shafiei N, Safarinejad S. 2010. An Open ...
  • Safarinejad  R, Shafiei  N, Safarinejad  S. 2011. A Prospective Double‐Blind ...
  • Shamsa  A, Hosseinzadeh H, Molaei M, Shakeri  T, Rajabi  O. ...
  • Sina  I. 2005. Al-Qanun Fi Al-Tibb [The Canon of Medicine]. ...
  • Smith  R, Tanagho  A, Mcaninch  W. 2008. Smith s General ...
  • Tonkaboni  M. 2011. Tohfato-Almomenin (Tohfehe-Hakim Momen). ...
  • Verma  S, and  Bordia  A. 1998. Antioxidant Property of Saffron ...
  • Wang X, Sharma K, Sikka  C, Thomas J, Falcone T, ...
  • Whiteford  M, and  Gonzalez  L. 1995. Stigma: The Hidden Burden ...
  • Zini  A, Lamirande E, Gagnon  C. 1993. Reactive Oxygen Species ...

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.

Scientometrics

The specifications of the publisher center of this Paper are as follows:
Type of center: علوم پزشکی
Paper count: 8,323
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.

Support