Synthesis of 2-arylbenzimidazole derivatives using nano montmorillonite clay as an efficient catalyst

Benzimidazoles are among the most important nitrogen-containing heterocyclic compounds that have many pharmaceutical applications, including antitumor, anticancer, anticorrosive, antibacterial, irritant and enzymatic interceptors. In this research, the synthesis of benzimidazoles by using o-phenylenediamine and aldehyde derivatives in the presence of the nano montemurillonite in solvent-free and room temperature conditions has been investigated. All products with relatively good yields were identified by spectroscopic and melting point methods.

Keywords:

Nano montemurillonite clay , benzimidazoles , solvent-free conditions , heterocyclic compounds