The changes in platelets indices in women with a recurrent miscarriage history in the Kosar Hospital

Background: Recurrent miscarriage (RM) is explained as three or more consecutive pregnancy losses occurring before 20 weeks post menstruation. The sterile inflammatory process in pregnancy physiology is requires for successful implantation of the conception. Platelets (PLT) are as acute-phase reactants. Since RPL is related with the inflammatory response, PLT indices may be applied for prediction of RM. Our objective is to evaluate the changes in PLT indices in women with a recurrent miscarriage history. Patients and Methods: For this cross sectional study data were evaluated from 25 recurrent miscarriage patient and 25 healthy controls between November 2015 and November 2016. Inclusion and exclusion criteria’s were applied. The data from these participants were obtained by a check list and evaluate the Complete blood counts (at least 12 weeks after miscarriage). Both descriptive and statistical analysis methods were applied. (P value < 0.05) Results: Age range of subjects in this study was 30.37 ± 0.4 years and control group was 28± 5.0 years. MPV were 7.8± 3 fL in subjects and 8.6± 4.3 fL in controls groups. There was sta tistically significant differences between the subjects and control groups with regard to MPV and was not to age. (P value < 0.05), (P value > 0.05) Conclusions: Pregnancy was cause of hemostatic disturbances and raised thrombophilia risk. This status was causes obstetric complications such as abortions. Platelet volume is directly related to increased PLTproduction. Therefore evaluation PLT indices are cost-effective, easily measurable,and practical markers for the prediction of RM

Keywords:

Mean platelet volume , Recurrent miscarriage