Fabrication and characterization of nanocomposites Mg-Al-Graphene for bone regeneration application

IntrodutionThe bone constitutes the skeleton of the human body and is one of the main tissues in the body. Millions of people suffer from bone diseases every year in the world. In recent years, implants have been developed to repair and fix bone fractures. While the primarily implant used in human body was non-degradable implants, the secondary surgery led to research on implants with good mechanical and biological properties. In this respect, magnesium and its alloys potentially be applied as degradable metallic materials in orthopedic implants due to their degradability and resemblance to human cortical bone. However, the high corrosion rate and accumulation of hydrogen gas upon degradation hinders its clinical application.ObjectiveIn this study, we introduced a new approach to control the corrosion rate. MethodsIn this method, Mg–Al–graphene oxide nanocomposites were synthesized using the powder metallurgy method. The effect of Al and graphene oxides addition in to pure Mg was examined through corrosion rate and hardness tests. The graphene oxide content was 0.18 wt.% and Al content was 1 wt.%. Mechanical properties and corrosion rate of synthesized nanocomposites proved to be better than pure magnesium and Mg–alloy.ResultsTherefore, it is expected that biodegradable implants of Mg-1.0Al-0.18Geraphen nanocomposies with a controllable biological and mechanical properties is suitable for damaged bone tissue and leads to stimulation, repair and reconstruction of bone tissue

Keywords:

Bone biodegradable implants , Nano-composites , Corrosion , Biocompatibility