Echocardiographic Evaluation of Prevalence of Pulmonary Hypertension in Beta thalassemia major: a cross sectional study
Publish place: Third International Congress of Pulmonary Diseases
Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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VLMED03_002
تاریخ نمایه سازی: 21 مرداد 1398
Abstract:
Introduction: Pulmonary hypertension is a common complication associated with thalassemia syndromes. It may play an important role in the pathogenesis of right ventricle failure. Hence, the true prevalence of pulmonary hypertension in patients with thalassemia major remains unclear and has been report between 2% and 79%.Materials and methods: In total, 70 patients with thalassemia major were initially examined. Patients with valvular left heart disease; congenital heart diseases, such as atrial septal defect (ASD) and ventricular septal defect (VSD); left heart failure; and chronic embolism were excluded. All patients with thalassemia major underwent echocardiography. Based on the TRV, the patients were divided into three groups, i.e., low, medium, and high risk of pulmonary hypertension groups.Results: The mean age of the subjects was 24 years; 60.6% of the subjects were males, and 39.4% of the subjects were females. Overall, 3 (4.5%) subjects were considered at a high risk of pulmonary hypertension. The mean hemoglobin level in the patients with a high probability of pulmonary hypertension was 8.2 gr/dl, and that in the patients with a low or medium probability of pulmonary hypertension was 9.1 gr/dl. No significant difference was observed between the groups (p=0.059).Conclusion: Compared with previous studies, the prevalence of pulmonary hypertension in patients with thalassemia major was low
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Authors
Farid Rashidi
Tuberclosis and lung disease research center, Tabriz University of Medical Sciences, Tabriz, Iran
Hossein Sate,
Departments of Cardiology, Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Ali Mohammadi
Tuberclosis and lung disease research center, Tabriz University of Medical Sciences, Tabriz, Iran
Ata Koohi
Tuberclosis and lung disease research center, Tabriz University of Medical Sciences, Tabriz, Iran