Synthesis and Characterization of Iron Oxide Nanoparticles via co-Precipitation and Reverse Micelles Methods in the Biological Applications

In recent years, the wide applications of iron oxide nanoparticles in the field of medicine, imagingand drug delivery increase the usage of this product in the medicine and pharmacy. Dueto the significance of this issue, the synthesis of these nanoparticles is vitally important.Among the synthetic methods of nanoparticles, the simplest procedure is co-precipitation inwhich in the presence of an alkali, divalent and trivalent iron salts react with each other [1-3].However, based upon the control of size in the clinical applications, the reverse micellesmethod seems valuable. In this procedure, using surfactant produces the iron oxide nanoparticleswith desired sizes. This can be due to the control of surfactant amounts and its proportionwith starting materials, divalent iron salts. It should be mentioned that this method cannot beapplicable about the pH procedure and trivalent iron salts. In this research, some characterizationspectrum of nanoparticles has been compared to result in the best condition of coprecipitationmethod with the control and investigation of nanoparticles production procedures.