Mahdieh Sanclooli - Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴,Zahedan, Iran
Nourallah Hazeri - Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴,Zahedan, Iran
Maryam Kochakzay - Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴,Zahedan, Iran
Maryam Shokoohian - Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran

Synthesis of heterocycles has always been a topic of great interest owing to the agricultural,pharmacological, and industrial significance of the majority of heterocyclic structures [1].Among an immense variety of N-heterocyclic compounds, acridine moieties are preeminentdue to their multiple pharmacological and biological activities [2]. Many procedures havebeen extended for synthesis of these scaffolds via hantzch reaction. However, a vast survey ofthe literature disclosed that there are a few synthetic methods for construction of pyrroloacridineswith three-component reaction of dimedone, various anilines, and isatin [3]. Hence, wedeveloped the synthesis of medicinally important 2-arylpyrrolo[2,3,4-kl]acridin-1(2H)-onesby an efficient and convenient approach of three-component reactions of dimedone, variousanilines, and isatin in the presence of PTSA as environmentally benign and effective catalyst.This work presented here has the merits of environmental friendliness, easy operation, simplework-up, excellent yields. Chemical structures of all molecules were characterized by spectraldata and elemental analysis.