Four-component synthesis of highly substituted dihydro-2-oxypyrrole derivatives catalyzed by cadmium acetate dihydrate as an efficient catalyst

We have studied the catalytic ability of cadmium acetate dihydrate as a mild, environmentally benign nature and economical catalyst for the multi-component efficient synthesis of biologically active highly substituted dihydro-2-oxypyrrole derivatives with excellent yields and short reaction times. The most important advantages of this procedure are mild, non-toxic and low-cost catalyst, one-pot, environmentally benign, simple operational procedures and highly efficient conditions.

Keywords:

Highly substituted dihydro-2-oxypyrroles , Cadmium acetate dihydrate (Cd(OAc)2·2H2O) , Readily available catalyst , High atom-economy.