Seyed Ali Tabatabaei - MSc student, Tarbiat Modares University
Mohammad Zabetian Targhi - Assistant Professor of Mechanical Engineering, Tarbiat Modares University

Today, with the progress of science and technology, in order to comprehensively examine the common diseases in the world, in the fields of medicine and engineering, we are witnessing an increase in studies on the separation of biological elements on microfluidic chips. Isolation of biological elements is important in order to identify and study particles in order to diagnose, improve or treat diseases andimprove health status. The separation of biological elements, such as cancer cells, can have a special impact on the process of sampling, medical diagnosis, and testing. The use of active and passive mechanical methods, including the use of externalfields, like a magnetic field or governing flow parameters, can play a special role in this situation.In this article, we try to design and numerical study a microfluidic microchip for particle separation with a combined active and passive method. With using inertia and magnet technique together, we could improve efficiency and purify of separation

Microfluidics, Passive separation, Active separation, Inertia, Circulate Tumor Cell