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Title

A novel and efficient synthesis of bisindolyl methanes with using silica-supported 3-(triethoxysilyl) propane-1-ammonium chloride as reusable catalyst under solvent free conditions

Year: 1395
COI: JR_ICC-4-4_007
Language: EnglishView: 152
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Authors

Mohammad Reza Poor Heravi - Department of Chemistry, Payame Noor University, Abhar, Iran
Aazam Monfared Monfared - Department of Chemistry, Payame Noor University, P.O. Box 19395-3697, Tehran, Iran
Masoumeh Ahmadi - Department of Chemistry, Payame Noor University, P.O. Box 19395-3697, Tehran, Iran

Abstract:

A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different conditions and optimized. The use of just 0.02 g of (silica gel-ammonium salt) is sufficient. The reaction was carried out at 110 °C under thermal condition. This method, including some advantages such as mild reaction condition, easy work-up, and recoverable and reusable catalyst.A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different conditions and optimized. The use of just 0.02 g of (silica gel-ammonium salt) is sufficient. The reaction was carried out at 110 °C under thermal condition. This method, including some advantages such as mild reaction condition, easy work-up, and recoverable and reusable catalyst..

Keywords:

Bis(indolyl)methanes, multicomponent reactions, silica-supported 3-(triethoxysilyl) propane-1-ammonium chloride, solvent-free conditions

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This Paper COI Code is JR_ICC-4-4_007. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

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Poor Heravi, Mohammad Reza and Monfared, Aazam Monfared and Ahmadi, Masoumeh,1395,A novel and efficient synthesis of bisindolyl methanes with using silica-supported 3-(triethoxysilyl) propane-1-ammonium chloride as reusable catalyst under solvent free conditions,,,,,https://civilica.com/doc/931415

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