Abhijeet Somwanshi - Research Centre and Post Graduate Department of Chemistry, PadmashriVikhePatil College of Arts, Science and Commerce Pravaranagar At./Po. Lonikd. Tal.Rahata. Dist. Ahmednagar. ۴۱۳۷۱۳. (MS). India. (Affiliated to SavitribaiPhule Pune University,
Yashwant Pandit - Applied Chemistry Division, DIAT-DRDO, Girinagar, Pune. ۴۱۱۰۲۵.(MS) India.
Akash Gholap - Research Centre and Post Graduate Department of Chemistry, PadmashriVikhe Patil College of Arts, Science and Commerce Pravaranagar At./Po. Lonikd. Tal.Rahata. Dist. Ahmednagar. ۴۱۳۷۱۳. (MS). India. (Affiliated to Savitribai Phule Pune University,
Rushikesh Ghogare - Research Centre and Post Graduate Department of Chemistry, Padmashri Vikhe Patil College of Arts, Science and Commerce Pravaranagar At./Po. Lonikd. Tal.Rahata. Dist. Ahmednagar. ۴۱۳۷۱۳. (MS). India. (Affiliated to Savitribai Phule Pune University,

An efficient one pot multi component synthesis of 1, 4-Polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction using lanthanum chloride heptahydrate (LaCl3.7H2O) from an aromatic aldehyde, ethyl acetoacetate, dimedone and ammonium acetate as a nitrogen precursor in ethanol at room temperature is described. In the present work we report lanthanum chloride heptahydrate remarkably non-toxic in nature and ease of handling we explored the utility of lanthanum chloride as a catalyst for the synthesis of 1, 4-polyhydroquinoline derivatives. We newly report p-N, N-dimethylamino-cinnamaldehyde and m-chlorobenzaldehyde for the synthesis of 1, 4-Polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction and was characterized by IR and 1HNMR spectroscopic methods.

Hantzsch reaction, lanthanum chloride heptahydrate, Polyhydroquinoline derivatives, aromatic aldehydes