Farzaneh Mohamadpour - Young Researchers and Elite Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran

An efficient and readily aluminium oxide (Al2O3) for the synthesis spiro-4H-pyran derivatives has been accomplished via one-pot condensation of isatin, malononitrile and different reagents including 1, 3-dicrbonyl compounds, naphthol and 4-hydroxycumarin. The notable advantages of the present procedure are: operational simplicity, solvent-free conditions, environmentally benign nature, low-cost and non-toxic catalyst, short reaction times and good yields.

Aluminium oxide (Al2O3); Spiro-4H-pyran derivatives; Operational simplicity; Environmentally benign nature conditions.