Comparison of Vitamin D Level in Preterm and Term Infant–Mother Pairs: A Brief Study
Publish place: The Iranian Journal of Neonatology، Vol: 7، Issue: 1
Publish Year: 1395
نوع سند: مقاله ژورنالی
زبان: English
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JR_IRJN-7-1_006
تاریخ نمایه سازی: 9 مهر 1398
Abstract:
Background: Recent studies have demonstrated the high prevalence of vitamin D deficiency in the general population. Pregnancy and preterm delivery are known as risk factors for vitamin D deficiency. Consequently, vitamin D level in women with preterm deliveries might vary from those with term pregnancies. In this study, we aimed to compare vitamin D level in term and preterm infant–mother pairs. Methods: This cross-sectional study was conducted in the neonatal intensive care unit of Mahdieh Hospital in Tehran, Iran in 2013. Serum level of 25-hydroxy vitamin D in preterm infant-mother pairs (≤ 32 weeks of gestation and birth weight ≤ 1500 g) was compared with term infant-mother pairs within the first 24 hours after delivery. Results: In total, 62 infant-mother pairs were recruited in this study, including 33 preterm (53.2%) and 29 term (46.8%) newborns; overall, 32 (51.6%) infants were male. the mean maternal age was 27.3 years in the preterm group and 26.4 years in the term group. The mean serum vitamin D level in preterm infants was 13.91 ng/ml. In the preterm group, vitamin D level was within the range of 4-59 ng/ml in newborns and 8-62 ng/ml in mothers. In the term group, the mean vitamin D level was 13.39 in infants and 13.7 ng/ml in mothers. In total, 48.5% and 65.5% of preterm and term groups had vitamin D deficiency, respectively. Among all newborns, 56% had vitamin D deficiency, although the difference between term and preterm neonates was not statistically significant. Also, there was no significant correlation between the infants’ serum vitamin D level and birth weight. Based on the findings, serum vitamin D levels in mothers and newborns were significantly correlated (P<0.001). Conclusion: According to the present study, there was no significant correlation between gestational age and vitamin D level in infant-mother pairs; however, vitamin D levels in mothers and newborns were significantly correlated.
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Authors
Minoo Fallahi
Neonatal Health Research Center (NHRC), Shahid Beheshti University of Medical Sciences, Mofid Hospital, Tehran, Iran
Abolfazl Afjeh
Neonatal Health Research Center (NHRC), Shahid Beheshti University of Medical Sciences, Mofid Hospital, Tehran, Iran
Hedieh Saneifard
Shahid Beheshti University of Medical Sciences, Mofid Hospital, Tehran, Iran
Navid Namazi
Neonatal Health Research Center (NHRC), Shahid Beheshti University of Medical Sciences, Mofid Hospital, Tehran, Iran
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