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Title

Comparison of side effect of survanta and curosurf in decreasing mortality due to respiratory distress syndrome (RDS) in premature infants admitted in NICU of Ghaem Hospital On 2006-2008

مجله علمی ناباروری ایران، دوره: 4، شماره: 3
Year: 1392
COI: JR_IRJN-4-3_002
Language: EnglishView: 222
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Authors

Reza Saeedi - Department of pediatrics, School of Medicine, Mashhad university of medical sciences, Mashhad, Iran
Abdolkarim Hamedi - Department of pediatrics, School of Medicine, Mashhad university of medical sciences, Mashhad, Iran
Ali Javadi - Department of pediatrics, School of Medicine, Mashhad university of medical sciences, Mashhad, Iran
Mahbobeh Gholami Robatsangi - Department of Nursing, faculty member of neyshabur university of medical sciences, Neyshabur, Iran

Abstract:

Background: Using of natural and synthetic surfactant is a rescue treatment for respiratory distress syndrome. In Iran, Survanta and Curosurf are the most frequent used natural surfactant preparations. We compared the clinical response and safety of two surfactants poractant alpha (Curosurf) and beractant (Survanta) for treatment of respiratory distress syndrome (RDS) in preterm infants. Method:This study was a clinical trial study that performed during a 2-year period in Ghaem Center s neonatal care unit.Sample size was calculated with 95% confidence and power 80. 104 premature infants were treated with surfactant, 74 in survanta group and 30 in Curosurf group,. The differences between the two groups were assessed by ANOVA or the calculation of relative risks. Results: There were no statistically significant differences between infants treated with S and C in mean gestational age (30.58 vs. 29.00 weeks) and birth weight (1388 vs.1330 g). Also there was no significant difference between groups,  incidence at 28th day of Bronchopulmunary dysplasia (%40.5 vs. %40), Intra ventricular hemorrhage III/IV (%13/5 vs. % 13/3), pneumothorax (%20 vs. % 20), Patent ductus arteriosis (%28/3 vs. % 20), and death (%28 vs. % 26/6). Conclusion:This study concluded that Survanta and Curosurf are similar in treatment of neonatal respiratory distress syndrome.

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This Paper COI Code is JR_IRJN-4-3_002. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/935374/

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Saeedi, Reza and Hamedi, Abdolkarim and Javadi, Ali and Gholami Robatsangi, Mahbobeh,1392,Comparison of side effect of survanta and curosurf in decreasing mortality due to respiratory distress syndrome (RDS) in premature infants admitted in NICU of Ghaem Hospital On 2006-2008,https://civilica.com/doc/935374

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Type of center: علوم پزشکی
Paper count: 8,081
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