Evaluation of the effects of anticoagulant drugs on the rate of bleeding of oral surgeries and warfarin alternatives

Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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JR_INTJMI-7-1_001

تاریخ نمایه سازی: 15 مهر 1398

Abstract:

Introduction: Today, with advances in the treatment of cardiovascular patients such as intravascularstents, cardiac valves and intracavitary pacemakers and cardiac transplantation, many cardiovascularpatients should use anticoagulants such as warfarin, aspirin, Plavix and Sosix, Ticlopidine and otherdrugs. The aim of this study was to investigate the effects of coagulation drugs on the rate of bleeding oforal surgeries and warfarin alternative.Methods: For access to studies on anticoagulant drugs and their effect on the bleeding of oral surgery inheart patients, the PUBMED, MEDLINE, MAGIRAN, SID, ELMNET and GOOGLE databases havebeen used since 1998 to 2015. Keywords include oral surgery, anticoagulants, warfarin, dentistry andbleeding.Findings: In the investigations done on the studied articles, it seems that patients with anticoagulantdrugs that are supposed to undergo minor dental surgeries do not require discontinuation, dose reduction,or even control of coagulation factors and bleeding can only be controlled by local dental procedures suchas suturing, mouthwash, gel sponge. And the risk of severe complications in case of warfarin interruptionand thrombosis is more than uncontrolled bleeding from the teeth. There is also no need for alternativewarfarin medicines.Conclusion: The hazard of severe complications in case of warfarin interruption and thrombosis is morethan uncontrolled hemorrhage from the teeth. There is also no need for alternative warfarin treatments.

Authors

Amirhosein Pakravan

Assistant Professor, Department of oral and maxillofacial surgery, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran

Tahmine Bamdadian

Assistant Professor, Department of prosthodontics, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran

Pouya Akbari

Dentistry Student, Faculty of Dentistry, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran

Arash Alimirzaei

Dentistry Student, Faculty of Dentistry, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran