Ahmad Reza Moosavi-Zare - Sayyed Jamaleddin Asadabadi University, Asadabad, ۶۵۴۱۸۶۱۸۴۱, I. R. Iran
Hamid Goudarziafshar - Sayyed Jamaleddin Asadabadi University, Asadabad, ۶۵۴۱۸۶۱۸۴۱, I. R. Iran
Zahra Jalilian - Sayyed Jamaleddin Asadabadi University, Asadabad, ۶۵۴۱۸۶۱۸۴۱, I. R. Iran

In this work, we have reported the preparation of pyrano[2,3-d]pyrimidine dione derivatives by the tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives at the presence of isonicotinic acid as an efficient organocatalyst.

Pyrano[2, 3-d]pyrimidine dione, Tandem reaction, Isonicotinic acid, Organocatalyst