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Title

Potentially Preventable Number of Cases and Deaths Associated with Pneumococcal Diseases and Haemophilus Influenzae in Iran during (2010-2013)

Year: 1396
COI: JR_INJPM-5-2_014
Language: EnglishView: 295
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Authors

Manoochehr Karami - Modeling of Non communicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Bahram Haghighi - Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
Alireza Soltanian - Department of Biostatistics, School of Public Health, Modeling of Noncommunicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Ardashir Khosravi - Ministry of Health and Medical Education, cardiovascular Research Center, Tehran University of Medical Sciences, Iran.

Abstract:

Background: Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) is a leading cause of bacterial pneumonia, meningitis, and sepsis in children under 5-year of age. This study aims to estimate potentially preventable number of cases and deaths caused by Hib and pneumococcal in Iran.Materials and Methods:We used the burden of diseases model estimates of the World Health Organization (WHO) to calculate the number of cases and deaths caused by Streptococcus pneumoniae and Haemophilus influenzae in children less than 5 years old. Efficacy of Hib and pneumococcal vaccine was obtained from literature. Vaccine coverage was cited of published report from Ministry of Health and Medical Education Iran (National Committee on Immunization). Hib and Streptococcus pneumoniae diseases burden was obtained from the WHO global burden of disease project.Results: We found that  the number of potentially preventable cases and deaths from meningitis caused by Hib among under five years old children in 2013 were 5,414 (95% confidence intervals [CI]: 2838, 11630), and 61 (95% CI: 31, 93), respectively. Estimated number of Streptococcus pneumoniae related pneumonia cases in 2010 and 2013 were 37,732 (95% CI: 22,183, 58,334), and 30,728 (95% CI: 17,023, 50,412), respectively. The corresponding values for pneumonia related deaths from Streptococcus pneumonia were 438 (95% CI: 257, 677), in 2010 and 356 (95% CI: 197, 586), in 2013.Conclusions: Findings favor the effects of both Hib and Pneumococcal conjugate vaccine (PCV) in reducing the burden of disease and death in Iran. Policy makers are advised to introduce PCV to National immunization program.

Keywords:

Children , Iran , Haemophilus influenzae type b , Immunization , Streptococcus pneumoniae

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This Paper COI Code is JR_INJPM-5-2_014. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/940255/

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Karami, Manoochehr and Haghighi, Bahram and Soltanian, Alireza and Khosravi, Ardashir,1396,Potentially Preventable Number of Cases and Deaths Associated with Pneumococcal Diseases and Haemophilus Influenzae in Iran during (2010-2013),https://civilica.com/doc/940255

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Type of center: علوم پزشکی
Paper count: 3,258
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