Ali Tayebi - PhD student nursing, Department of Medical Surgical Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Alireza Kasra Dehkordi - MSc in nursing, College of Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran
Abbas Ebadi - PhD Associate Professor, Behavioral Sciences Research Center and Faculty Nursing, Tehran, Iran
Hedayat Sahraei - PhD Professor in neuroscience, Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Background: Depression, anxiety and stress are common among hemodialysis patients affecting their mental health and quality of life, leading to multiple dysfunctions. Anti-anxiety effects of aromatherapy, as one of the domains of complementary medicine, have been investigated in several studies. Aim: Investigation of the effect of aromatherapy with lavender essential oil on depression, anxiety and stress rates in hemodialysis patients. Methods: This study was a randomized controlled clinical trial performed on 60 patients undergoing hemodialysis in Tehran, Iran in 2014. The patients were randomly divided into intervention and control groups. To measure the rate of depression, anxiety and stress, the Depression Anxiety Stress Scales-21 was used. In the intervention group, the patients were asked to inhale the lavender essential oil smeared on a piece of cloth (three drops of oil) for one hour during the hemodialysis procedure. After 4 weeks, the rates of depression, anxiety and stress were re-measured. Data analysis was performed by SPSS software version 14 using chi-square, Wilcoxon and Mann-Whitney U statistical tests. Results: In this study, 33(60%) of the participants were male, and 53(96.4%) were married.  After the intervention, the scores of depression (P<0.001) and stress (P<0.04) significantly decreased in the intervention group in comparison with control group; but the reduction in the anxiety score was not statistically significant. Conclusion: Aromatherapy with lavender essential oil might reduce depression and stress among hemodialysis patients. Therefore, this method can be used as a complementary method with less complication to improve the quality of life of these patients.

Anxiety, Depression, Aromatherapy, hemodialysis, Lavender