Immediate dilation of a tight or stenotic cervix by intra-procedural administration of hyoscine butylbromide: A clinical trial

Background: Cervical dilation is indicated prior to performing various gynecologicalprocedures. However, gynecologists are at times confronted with a stenotic or tightcervix, resistant to dilation. This can be problematic particularly when cervical ripeninghas not been attempted hours before the start of the procedure.Objective: The objective of this study is to investigate the efficacy of administration ofhyoscine butylbromide for cervical dilation for immediate dilation of the tight or stenoticcervix.Materials and Methods: In this clinical trial study, a population of 40 women, aged20-70 yr with stenotic cervix, evidenced by resistance to pass dilator #2 through theircervical canal were compared. Cervical patency was assessed 10 min following intracervicalcanal instillation of hyoscine butylbromide.Results: Cervical width of 57.5% of patients became wider, as evidenced by passage ofthe number 4 Hegar dilator through the cervical canal without resistance. IndependentT-tests did not reveal any statistically significant difference between the two groupsbased on their age. Fisher Exact test revealed a statistically significant differencebetween the two groups based on the prior route of delivery, with a more statisticallysignificant response in patients who had vaginal deliveries.Conclusion: Intra-cervical canal instillation of hyoscine butylbromide is effective inimmediate dilation of the tight or stenotic cervix during intra-uterine procedures.

Keywords:

Hyoscine butylbromide , Cervical dilatation , Cervical ripening