Primary Ovarian Insufficiency and ART

Background: Primary ovarian insufficiency (POI) is a disease with gradual onset, in which the function, activity and follicles of the ovaries diminish before the age of 40. The prevalence is 1%. The disease is due to various causes such as autoimmune diseases, chemotherapy, radiotherapy,genetic disorder and turn-er syndrome.Materials and Methods: A narrative review was performed within articles published a PubMed , Elsevier , SID and original text books to reach the aim.Results: Clinical signs in primary ovarian insufficiency is amenorrhea before the age of 40, hot flashes, anxiety, depres-sion are fatigue. Primary ovarian insufficiency can be detected by using laboratory criteria and ultrasound techniques. Labora-tory Criteria are Increased serum Follicle stimulating hormone (FSH) levels above 40 mIu / ml and decreased serum Anti-Mullerian Hormone(AMH) levels. women with ovarian failure have no antral folliclesand size of ovaries are less than normal . It must be considered ultrasonography, specially vaginal sonog-raphe in detecting the follicles has major role.Conclusion: A we women with primary ovarin insufficiency (POI) have less chance for pregnancy and they most not waste the time .

Keywords:

Primary Ovarian Insufficiency , Assisted Reproduc-tive Technology , Infertility