Evaluation of the Prevalence of Multiple Sclerosis and its Important Risk Factors in Iran from 2005 through 2018: a Systematic Review

Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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NIMED03_178

تاریخ نمایه سازی: 7 آبان 1398

Abstract:

Multiple sclerosis is a demyelinating disease which is the most common immune-mediated disorder. The epidemiology of MS is vary from region to region in Iran. but several studies show that this disease has been increasing all over the country. In this study the aim was to provide a comprehensive review, regarding the prevalence of MS across Iran. Materials and Methods: The present study uses systematic searches of articles in the internal database (SID, Iran Medex and Magiran) and external authoritative databases (Google Scholar, Pub Med, Science Direct, MEDLINE, CINAHL and EMBASE) using keywords including prevalence , Iranian , Multiple Sclerosis and Incidence have been gathered since2005 to 2018. In this study 62 articles were collected. Finally, 16 studies were used. Results: The prevalence of MS in Iran according to the articles ranged from 14 in 100,000 to 116 in 100,000 people. The highest prevalence was in Tehran in 2015 (115.94 per100,000) and the lowest prevalence in Sistan-Baluchistan (13.9 per 100,000) .The prevalence of MS in Iran has increased in recent decades, which can be attributed to air pollution. Also among Iranian relatives, people with Lor’s parents are more likely to have this disease compareto other ethnicties. In addition, the heterogeneity of the ethnicity of the parents, increases the risk of MS .The prevalence rate in women is about three times as high as in men in the last decade.The high prevalence in women may have association with gender issues such as theonset of menstruation, the age of the first pregnancy, and use of OCPs. Another factor of this disease is vitamin D deficiency in women due to lifestyle in Iran and less exposure to sunlight. Conclusion: Due to the relatively high prevalence of this disease, it is important to do the necessary actions to prevent the disease. Also, people with vitamin D deficiency, which is one of the predisposing factors, can be cured. According to the findings, inheritance is one of the factors of the disease that health care administrators should identify susceptible families,and advise them to take preventive and therapeutic measures. Also, due to the high prevalence of women, it is necessary for authorities to pay more attention to women.

Authors

Parisa Mamivand

Research Committee, kashan University of Medical Sciences, Kashan, Iran

Arman Jafari

Shoushtar Faculty of Medical Sciences, Shoushtar, Iran