The Diagnostic Accuracy of 3-Dimensional Saline Infusion Transvaginal Ultrasound 3-D SIS in the Distinction Between Septate and Bicornuate Uteri

Backgrounds: The main objective was first to evaluate the diagnostic accuracy of Three- dimensional saline infusion transvaginal ultrasound (3-D SIS) in the evaluation of uterine contour and cavity, and second, to analysis the level of agreement in the results between this method and combined diagnostic laparoscopy/ hysteroscopy as a gold standard.Material and method: In a double blind prospective study, 100 reproductive age (30.19 ± 2.34) women with history of spontaneous abortion (57%) or candidate for assisted reproductive technology procedures (43%) and a suspected diagnosis of congenital uterine anomalies by hysterosalpingography were enrolled. The patients underwent (3-D SIS) and hysteroscopy with laparoscopy to establish the final diagnosis. The findings of two procedures were compared.Result: The accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of (3-D SIS) in diagnosis of uterine anomalies were 98.6, 100, 96.77, 97.66, 100%, respectively. The accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) in the differentiation of septate uterus from bicornuate uterus were 100%.Conclusion: There is a close correlation between the findings of (3-D SIS) and laparoscopy performed concurrently with hysteroscopy for the diagnosis of congenital uterine anomalies. (Three-D SIS) could be considered as an accurate procedure to assess uterine contour and cavity .This modality have the potential to become the gold standard in distinction between septate and bicornuate uteri