Wound Healing Effect of Tea Tree Oil on Methicillin Resistant Staphylococcus aureus (MRSA): an Animal Study

Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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ICCM13_145

تاریخ نمایه سازی: 25 آبان 1398

Abstract:

Background and Objectives: Tea tree oil (TTO), or melaleuca oil, is an essential oil with a fresh camphoraceous odor and a color that ranges from pale yellow to clear. It has been promising as an antimicrobial agent. It is said that it can be effective in a variety of dermatologic conditions, including dandruff, acne, lice, herpes, and other skin infections. The major goal of this study was to investigate antimicrobial and wound healing effects of tea tree oil in rabbits. Materials and methods: A total of twenty white New Zealand rabbits were divided into two groups in which number of males and females was equal. In the first group, a sterile wound was created by burning the skin. In the second group wounds were infected by Staphylococcus aureus (MRSA) using McFarland tubes. For each wound one drop of Staphylococcus aureus was spilled. Results: In each group two subjects were designated as control. Then, sampling was done on seventh, fifteenth and twenty first days. Samples were both pathologically and morphologically studied. Statistical analysis was performed using the χ2 test and Fisher s exact test. Conclusion: Infected subjects were all healed. Although amongst the first group, in which a sterile burn wound was created, females showed better results.

Authors

Fateme Sadat Musavi

Young researcher and elite club, Urmia branch, Islamic Azad University, Urmia Iran