Apoptotic and Autophagic modulation by nicotine
عنوان مقاله: Apoptotic and Autophagic modulation by nicotine
شناسه ملی مقاله: JR_IJABBR-7-3_008
منتشر شده در شماره 3 دوره 7 فصل در سال 1398
شناسه ملی مقاله: JR_IJABBR-7-3_008
منتشر شده در شماره 3 دوره 7 فصل در سال 1398
مشخصات نویسندگان مقاله:
Zahra Ahmadi - Department of basic science, Faculty of veterinary medicine, Islamic Azad Branch, Univeristy of Shushtar, Khuzestan-Iran
Milad Ashrafizadeh - ۲Department of basic science, Faculty of veterinary medicine, University of Tabriz, Tabriz-Iran
Melika Forouzan - Department of basic science, veterinary medicine faculty, Shushtar university, Khuzestan-Iran
خلاصه مقاله:
Zahra Ahmadi - Department of basic science, Faculty of veterinary medicine, Islamic Azad Branch, Univeristy of Shushtar, Khuzestan-Iran
Milad Ashrafizadeh - ۲Department of basic science, Faculty of veterinary medicine, University of Tabriz, Tabriz-Iran
Melika Forouzan - Department of basic science, veterinary medicine faculty, Shushtar university, Khuzestan-Iran
Cigarette smoking is growing and nicotine is considered as the most adverse agent in the cigarette smoking. Nicotine is an alkaloid and forms 90% of alkaloids of cigarette. Nicotine is accountable for creating disorders and cancers such as lung cancer, heart disease and chronic lung disease. Nicotine can be considered as an autophagy and apoptosis inducer which can either directly or indirectly stimulate apoptosis and autophagy. Apoptosis is the programmed cell death and oxidative stress in the most known inducer of apoptosis. However, physicochemical stresses, free radicals and removing of nutrients are other factors which induce apoptosis. Autophagy plays the role of recycling which mainly attacks damaged and aged cells and organelles. In this review, we investigate the effect of nicotine on these pathways.
کلمات کلیدی: Nicotine, Apoptosis, autophagy, Fate
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/959681/