Screening for Celiac Disease Using Anti Tissue Transglutaminase in Patients with Esophageal SCC between 2004 and 2009

Publish Year: 1394
نوع سند: مقاله ژورنالی
زبان: English
View: 295

This Paper With 5 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_JCTM-3-1_002

تاریخ نمایه سازی: 4 آذر 1398

Abstract:

  Introduction: Esophageal Squamous-Cell Carcinoma (SCC) is one of the most common malignancies in Iran. To reduce the incidence of esophageal SCC, it is important to recognize the controllable risk factors and prevent them. Celiac disease is widely known as a possible risk factor for esophageal SCC.  Thus, we decided to assess the frequency of celiac disease in esophageal SCC patients in North east of Iran in order to suggest correlation between two diseases. Materials and Methods: In a Cross-sectional study one hundred and forty-three cases of esophageal SCC were examined for anti tissue transglutaminase antibody (anti-tTG) between the years 2004 and 2009 in Ghaem and Omid Hospitals of Mashhad University of Medical Sciences, Iran. The enzyme-linked immunosorbent assay was the test of choice in this study since it provides the sensitivity and specificity needed for the diagnosis and screening of celiac disease. The results of this test were compared with those of the control group which were compatible in terms of sex and age. Data were analyzed through SPSS software and statistical analysis such as x2, exact x2 and T-test. Results:19.6% patients (SCC) had positive anti-tTG (> 20) which was significantly different to 7.9% in control group (p -value=0.005). Comparing age groups of patients for positive anti_tTG using exact x square test showed significant difference in patients with Conclusion: There seems to be a correlation between positive anti_tTG and esophageal SCC; that is to say, celiac disease might play a role in the earlier manifestations of esophageal SCC.

Authors

Hasan Vosoughinia

Gastroenterologist, Department of Gastroenterology and Hepatology, Mashhad University of Medical Sciences, Mashhad, Iran

Seyed Amir AleDavood

Oncologist, Department of Radiotherapy and Oncology, Mashhad University of Medical Sciences, Mashhad, Iran

Kamran Ghaffarzadehgan

Anatomo Clinical pathologist, Razavi Hospital, Mashhad, Iran

Mohammadtaghi shakeri

Community Medicine Specialist, Department of Epidemiology & Social Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • Fleischer D, Lawrence S; tumors of the esophagus. In: Sleisenger ...
  • Norat, T. and E. Riboli, Fruit and vegetable consumption and ...
  • P.U. Cook-Mozaffari, F. Azordegan, N.E. Day, A.Ressicaud, C. Sabai, B. ...
  • A. Pourshams, Saadatian-Elahi M, Nouraie M, Malekshah AF, Rakhshani N, ...
  • Enzyinger PC, Mayer RJ. Esophageal cancer. NEJM 2003; 349; 23: ...
  • Lee, Y.C., Marron M, Benhamou S, Bouchardy C, Ahrens W, ...
  • Freedman, N.D., Abnet CC, Leitzmann MF, Mouw T, Subar AF, ...
  • Parkin, D.M. Tobacco-attributable cancer burden in the UK in 2010. ...
  • Lee, C.H., Lee JM, Wu DC, Hsu HK, Kao EL, ...
  • Zendehdel K, Nyrén O, Edberg A, Ye W: Risk of esophageal adenocarcinoma in    achalasia patients, a retrospective cohort ...
  • Ghavamzadeh A, Moussavi A, Jahani M, Rastegarpanah M, Iravani M.  ...
  • Askling J, Linet M, Gridley G, Halstensen TS.    Cancer ...
  • Frrgusen A, Kingstone K. Celiac disease and malignancies. Acta Pediatr. ...
  • Lightdale CJ, Winawer SJ. Screening diagnosis and Staging of esophageal ...
  • West J, Logan RF, Hill PG, Lloyd A, Lewis S, ...
  • Peter H.R. Green, M.D.Celiac Disease.  Et al. Engl J Med ...
  • Rostami Nejad M, Rostami K, Emami M, Zali M, Malekzadeh ...
  • Malek zadeh R. Shakeri R. Celiac disease in Iran.TUMJ 2007 ...
  • Saberi-Firouzi M, Omrani GR, Nejabat M, Mehrabani D, Khademolhosseini F. ...
  • Khoshnia M, Pourshams A. Celiac disease in Gonbad-Kavoos: Govaresh autumn ...
  • Tirgar-Fakheri H, MalekzadehR, Akbari MR, Sotoudeh M. Prevalence of Celiac ...
  • Akbari MR, Mohammadkhani A, fakheri H.  Screening of the adult ...
  • Rampertab SD, Pooran N. Trends in the presentation of celiac ...
  • Freeman HJ. Malignancy in celiac disease. J. New Gastroenterol 2009; ...
  • West J, Logan RF. Malignancy and mortality in people with ...
  • Card TR, West J. Risk of malignancy in diagnosed celiac ...
  • Green pH, Fleischauer AT, Bhagat G, Goyal R. Risk of ...
  • Collins SM, Hamilton JD. Small-bowel Malabsorption and gastrointestinal malignancy. Radiology ...
  • Holmes GK, Prior P. Malignancy in celiac disease-effect of a ...
  • Brottveit M, Lundin KE.  Cancer risk in celiac disease. Tidsskr ...
  • نمایش کامل مراجع