Synthesis and characterization of a new dione by Mannich reaction method containing Thiophene moiety with related macrocyclic ligands and complexes

The importance of the Mannich reaction relates to the fact that the products of this reaction, known as Mannich bases, the reaction provides a good method for C-C bondformation. It essentially consists of the condensation of an aldehyde (mostly formaldehyde) and an amine with a substrate possessing acidic hydrogen [1]. Thiophene is a heterocyclic compound consist of sulfur atom, it is aromatic as indicated by its extensive substitution reactions [2]. In this work a new diketone has prepared by using 2-Acetyle thiophene and Homopiperazine by Mannich reaction method (1) and related ligands were obtained by condensation of synthesized dione with 2, 6-diamino pyridine (2) or Bis(2-aminoethyl) amine (3). Mn2+ and Zn2+ complexes of these ligands were syntesised by using of perchlorate salts of these ions. The ketone and related ligands and complexes were investigated by elemental analysis, IR spectroscopy, 1H and 13CNMR and Mass analysis